P2Y1R Ligation Suppresses Th17 Cell Differentiation and Alleviates Colonic Inflammation in an AMPK-Dependent Manner

P2Y1 receptor is a G-protein-coupled receptor that plays a critical role in the immune response of inflammatory bowel diseases. However, its regulatory effects on CD4(+) T cell response have not been fully elucidated. The study aimed to characterize the role of P2Y1R in Th17 cell differentiation and...

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Detalles Bibliográficos
Autores principales: Chang, Yao-Yao, Huan, Qiu-Chan, Peng, Jiao, Bi, Wen-Chun, Zhai, Li-Xiang, Chen, Yan, Lamb, Jonathan R., Shen, Xiang-Chun, Bian, Zhao-Xiang, Wu, Hai-qiang, Cheng, Yong-Xian, Xiao, Hai-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866175/
https://www.ncbi.nlm.nih.gov/pubmed/35222397
http://dx.doi.org/10.3389/fimmu.2022.820524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866175/
https://www.ncbi.nlm.nih.gov/pubmed/35222397
http://dx.doi.org/10.3389/fimmu.2022.820524

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