Late-stage rescue of visually guided behavior in the context of a significantly remodeled retinitis pigmentosa mouse model

Patients with progressive neurodegenerative disorder retinitis pigmentosa (RP) are diagnosed in the midst of ongoing retinal degeneration and remodeling. Here, we used a Pde6b-deficient RP gene therapy mouse model to test whether treatment at late disease stages can halt photoreceptor degeneration a...

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Detalles Bibliográficos
Autores principales: Kajtna, Jacqueline, Tsang, Stephen H., Koch, Susanne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866266/
https://www.ncbi.nlm.nih.gov/pubmed/35195763
http://dx.doi.org/10.1007/s00018-022-04161-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866266/
https://www.ncbi.nlm.nih.gov/pubmed/35195763
http://dx.doi.org/10.1007/s00018-022-04161-0

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