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Late-stage rescue of visually guided behavior in the context of a significantly remodeled retinitis pigmentosa mouse model
Patients with progressive neurodegenerative disorder retinitis pigmentosa (RP) are diagnosed in the midst of ongoing retinal degeneration and remodeling. Here, we used a Pde6b-deficient RP gene therapy mouse model to test whether treatment at late disease stages can halt photoreceptor degeneration a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866266/ https://www.ncbi.nlm.nih.gov/pubmed/35195763 http://dx.doi.org/10.1007/s00018-022-04161-0 |