H3K27ac nucleosomes facilitate HMGN localization at regulatory sites to modulate chromatin binding of transcription factors

Nucleosomes containing acetylated H3K27 are a major epigenetic mark of active chromatin and identify cell-type specific chromatin regulatory regions which serve as binding sites for transcription factors. Here we show that the ubiquitous nucleosome binding proteins HMGN1 and HMGN2 bind preferentiall...

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Detalles Bibliográficos
Autores principales: Zhang, Shaofei, Postnikov, Yuri, Lobanov, Alexei, Furusawa, Takashi, Deng, Tao, Bustin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866397/
https://www.ncbi.nlm.nih.gov/pubmed/35197580
http://dx.doi.org/10.1038/s42003-022-03099-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866397/
https://www.ncbi.nlm.nih.gov/pubmed/35197580
http://dx.doi.org/10.1038/s42003-022-03099-0

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