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Fortilin interacts with TGF-β1 and prevents TGF-β receptor activation

Fortilin is a 172-amino acid multifunctional protein present in both intra- and extracellular spaces. Although fortilin binds and regulates various cellular proteins, the biological role of extracellular fortilin remains unknown. Here we report that fortilin specifically interacts with TGF-β1 and pr...

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Detalles Bibliográficos
Autores principales: Pinkaew, Decha, Martinez-Hackert, Erik, Jia, Wei, King, Matthew D., Miao, Fei, Enger, Nicole R., Silakit, Runglawan, Ramana, Kota, Chen, Shi-You, Fujise, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866402/
https://www.ncbi.nlm.nih.gov/pubmed/35197550
http://dx.doi.org/10.1038/s42003-022-03112-6