Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes

Large-scale biobank initiatives and commercial repositories store genomic data collected from millions of individuals, and tools to leverage the rapidly growing pool of health and genomic data in disease prevention are needed. Here, we describe the derivation and validation of genomics-enhanced risk...

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Detalles Bibliográficos
Autores principales: Tamlander, Max, Mars, Nina, Pirinen, Matti, Widén, Elisabeth, Ripatti, Samuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866413/
https://www.ncbi.nlm.nih.gov/pubmed/35197564
http://dx.doi.org/10.1038/s42003-021-02996-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866413/
https://www.ncbi.nlm.nih.gov/pubmed/35197564
http://dx.doi.org/10.1038/s42003-021-02996-0

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