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Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes
Large-scale biobank initiatives and commercial repositories store genomic data collected from millions of individuals, and tools to leverage the rapidly growing pool of health and genomic data in disease prevention are needed. Here, we describe the derivation and validation of genomics-enhanced risk...
Autores principales: | Tamlander, Max, Mars, Nina, Pirinen, Matti, Widén, Elisabeth, Ripatti, Samuli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866413/ https://www.ncbi.nlm.nih.gov/pubmed/35197564 http://dx.doi.org/10.1038/s42003-021-02996-0 |
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