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Data-driven design of targeted gene panels for estimating immunotherapy biomarkers
Tumour mutation burden and other exome-wide biomarkers are used to determine which patients will benefit from immunotherapy. However, the cost of whole exome sequencing limits the widespread use of such biomarkers. Here, we introduce a data-driven framework for the design of targeted gene panels for...
Autores principales: | Bradley, Jacob R., Cannings, Timothy I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866421/ https://www.ncbi.nlm.nih.gov/pubmed/35197525 http://dx.doi.org/10.1038/s42003-022-03098-1 |
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