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ADAMTS8 Promotes Cardiac Fibrosis Partly Through Activating EGFR Dependent Pathway

Myocardial infarction or pressure overload leads to cardiac fibrosis, the leading cause of heart failure. ADAMTS8 (A disintegrin and metalloproteinase with thrombospondin motifs 8) has been reported to be involved in many fibrosis-related diseases. However, the specific role of ADAMTS8 in cardiac fi...

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Detalles Bibliográficos
Autores principales: Zha, Yafang, Li, Yanyan, Ge, Zhuowang, Wang, Jian, Jiao, Yuheng, Zhang, Jiayan, Zhang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866452/
https://www.ncbi.nlm.nih.gov/pubmed/35224040
http://dx.doi.org/10.3389/fcvm.2022.797137