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Deep neural network prediction of genome-wide transcriptome signatures – beyond the Black-box

Prediction algorithms for protein or gene structures, including transcription factor binding from sequence information, have been transformative in understanding gene regulation. Here we ask whether human transcriptomic profiles can be predicted solely from the expression of transcription factors (T...

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Detalles Bibliográficos
Autores principales: Magnusson, Rasmus, Tegnér, Jesper N., Gustafsson, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866467/
https://www.ncbi.nlm.nih.gov/pubmed/35197482
http://dx.doi.org/10.1038/s41540-022-00218-9