Integrated bioinformatics analysis identifies established and novel TGFβ1-regulated genes modulated by anti-fibrotic drugs

Fibrosis is a leading cause of morbidity and mortality worldwide. Although fibrosis may involve different organ systems, transforming growth factor-β (TGFβ) has been established as a master regulator of fibrosis across organs. Pirfenidone and Nintedanib are the only currently-approved drugs to treat...

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Detalles Bibliográficos
Autores principales: Wilson, Ava C., Chiles, Joe, Ashish, Shah, Chanda, Diptiman, Kumar, Preeti L., Mobley, James A., Neptune, Enid R., Thannickal, Victor J., McDonald, Merry-Lynn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866468/
https://www.ncbi.nlm.nih.gov/pubmed/35197532
http://dx.doi.org/10.1038/s41598-022-07151-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866468/
https://www.ncbi.nlm.nih.gov/pubmed/35197532
http://dx.doi.org/10.1038/s41598-022-07151-1

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