Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer

Isoform-specific functions of Numb in the development of cancers, especially in the initiation of epithelial-to-mesenchymal transition (EMT) remains controversial. We study the specific function of Numb-PRRL isoform in activated EMT of pancreatic ductal adenocarcinoma (PC), which is distinguished fr...

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Detalles Bibliográficos
Autores principales: Sheng, Weiwei, Tang, Jingtong, Cao, Rongxian, Shi, Xiaoyang, Ma, Yuteng, Dong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866481/
https://www.ncbi.nlm.nih.gov/pubmed/35197444
http://dx.doi.org/10.1038/s41419-022-04609-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866481/
https://www.ncbi.nlm.nih.gov/pubmed/35197444
http://dx.doi.org/10.1038/s41419-022-04609-y

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