Cell surface nucleolin is a novel ADAMTS5 receptor mediating endothelial cell apoptosis

A Disintegrin and Metalloproteinase with ThromboSpondin motif (ADAMTS) 5 functions as an anti-angiogenic and anti-cancer protein independent of its metalloproteinase activity. Both full-length ADAMTS5 and TS5-p45, the autocatalytically cleaved C-terminal 45 kDa truncate of ADAMTS5, inhibits angiogen...

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Detalles Bibliográficos
Autores principales: Kirman, Dogan Can, Renganathan, Bhuvanasundar, Chui, Wai Kit, Chen, Ming Wei, Kaya, Neslihan Arife, Ge, Ruowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866485/
https://www.ncbi.nlm.nih.gov/pubmed/35197459
http://dx.doi.org/10.1038/s41419-022-04618-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866485/
https://www.ncbi.nlm.nih.gov/pubmed/35197459
http://dx.doi.org/10.1038/s41419-022-04618-x

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