Endothelial cell ferroptosis mediates monocrotaline-induced pulmonary hypertension in rats by modulating NLRP3 inflammasome activation

Inflammation triggers pulmonary vascular remodelling. Ferroptosis, a nonapoptotic form of cell death that is triggered by iron-dependent lipid peroxidation and contributes to the pathogenesis of several inflammation-related diseases, but its role in pulmonary hypertension (PH) has not been studied....

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Detalles Bibliográficos
Autores principales: Xie, Shan-Shan, Deng, Yan, Guo, Sheng-lan, Li, Jia-quan, Zhou, Ying-chuan, Liao, Juan, Wu, Dan-dan, Lan, Wei-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866506/
https://www.ncbi.nlm.nih.gov/pubmed/35197507
http://dx.doi.org/10.1038/s41598-022-06848-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866506/
https://www.ncbi.nlm.nih.gov/pubmed/35197507
http://dx.doi.org/10.1038/s41598-022-06848-7

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