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Evidence for a trap-and-flip mechanism in a proton-dependent lipid transporter

Transport of lipids across membranes is fundamental for diverse biological pathways in cells. Multiple ion-coupled transporters take part in lipid translocation, but their mechanisms remain largely unknown. Major facilitator superfamily (MFS) lipid transporters play central roles in cell wall synthe...

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Detalles Bibliográficos
Autores principales: Lambert, Elisabeth, Mehdipour, Ahmad Reza, Schmidt, Alexander, Hummer, Gerhard, Perez, Camilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866510/
https://www.ncbi.nlm.nih.gov/pubmed/35197476
http://dx.doi.org/10.1038/s41467-022-28361-1