PD-L1 mediates lung fibroblast to myofibroblast transition through Smad3 and β-catenin signaling pathways

Programmed death ligand-1 (PD-L1) is an immune checkpoint protein that has been linked with idiopathic pulmonary fibrosis (IPF) and fibroblast to myofibroblast transition (FMT). However, it remains largely unclear how PD-L1 mediates this process. We found significantly increased PD-L1 in the lungs o...

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Detalles Bibliográficos
Autores principales: Guo, Xia, Sunil, Christudas, Adeyanju, Oluwaseun, Parker, Andrew, Huang, Steven, Ikebe, Mitsuo, Tucker, Torry A., Idell, Steven, Qian, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866514/
https://www.ncbi.nlm.nih.gov/pubmed/35197539
http://dx.doi.org/10.1038/s41598-022-07044-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866514/
https://www.ncbi.nlm.nih.gov/pubmed/35197539
http://dx.doi.org/10.1038/s41598-022-07044-3

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