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Assessment of mouse-specific pharmacokinetics in kidneys based on (131)I activity measurements using micro-SPECT

BACKGROUND: In order to acquire accurate drug pharmacokinetic information, which is required for tissue dosimetry, micro-SPECT must be quantitative to allow for an accurate assessment of radioligand activity in the relevant tissue. This study investigates the feasibility of deriving accurate mouse-s...

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Detalles Bibliográficos
Autores principales: Vargas, Clarita Saldarriaga, Struelens, Lara, D’Huyvetter, Matthias, Caveliers, Vicky, Covens, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866625/
https://www.ncbi.nlm.nih.gov/pubmed/35195790
http://dx.doi.org/10.1186/s40658-022-00443-5