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Assessment of mouse-specific pharmacokinetics in kidneys based on (131)I activity measurements using micro-SPECT

BACKGROUND: In order to acquire accurate drug pharmacokinetic information, which is required for tissue dosimetry, micro-SPECT must be quantitative to allow for an accurate assessment of radioligand activity in the relevant tissue. This study investigates the feasibility of deriving accurate mouse-s...

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Detalles Bibliográficos
Autores principales:	Vargas, Clarita Saldarriaga, Struelens, Lara, D’Huyvetter, Matthias, Caveliers, Vicky, Covens, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866625/ https://www.ncbi.nlm.nih.gov/pubmed/35195790 http://dx.doi.org/10.1186/s40658-022-00443-5

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