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Therapeutic Antibodies Against Shiga Toxins: Trends and Perspectives

Shiga toxins (Stx) are AB(5)-type toxins, composed of five B subunits which bind to Gb(3) host cell receptors and an active A subunit, whose action on the ribosome leads to protein synthesis suppression. The two Stx types (Stx1 and Stx2) and their subtypes can be produced by Shiga toxin-producing Es...

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Detalles Bibliográficos
Autores principales: Henrique, Izabella de Macedo, Sacerdoti, Flavia, Ferreira, Raissa Lozzardo, Henrique, Camila, Amaral, Maria Marta, Piazza, Roxane Maria Fontes, Luz, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866733/
https://www.ncbi.nlm.nih.gov/pubmed/35223548
http://dx.doi.org/10.3389/fcimb.2022.825856