Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis

Ferroptosis, a type of cell death triggered by excessive accumulation of iron-dependent lipid peroxidation, possesses an excellent potential in cancer treatment. However, many colorectal cancer (CRC) cell lines are resistant to ferroptosis induced by erastin and RSL3, the classical ferroptotic induc...

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Detalles Bibliográficos
Autores principales: Hu, Qian, Wei, Wanhui, Wu, Daiqian, Huang, Fengxing, Li, Mengting, Li, Wenjie, Yin, Jingwen, Peng, Yanan, Lu, Yuanyuan, Zhao, Qiu, Liu, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866854/
https://www.ncbi.nlm.nih.gov/pubmed/35223839
http://dx.doi.org/10.3389/fcell.2022.810327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866854/
https://www.ncbi.nlm.nih.gov/pubmed/35223839
http://dx.doi.org/10.3389/fcell.2022.810327

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