Cargando…

Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis

Ferroptosis, a type of cell death triggered by excessive accumulation of iron-dependent lipid peroxidation, possesses an excellent potential in cancer treatment. However, many colorectal cancer (CRC) cell lines are resistant to ferroptosis induced by erastin and RSL3, the classical ferroptotic induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Qian, Wei, Wanhui, Wu, Daiqian, Huang, Fengxing, Li, Mengting, Li, Wenjie, Yin, Jingwen, Peng, Yanan, Lu, Yuanyuan, Zhao, Qiu, Liu, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866854/
https://www.ncbi.nlm.nih.gov/pubmed/35223839
http://dx.doi.org/10.3389/fcell.2022.810327

Ejemplares similares