Notch1 Modulation of Cellular Calcium Regulates Mitochondrial Metabolism and Anti-Apoptotic Activity in T-Regulatory Cells

As the major hub of metabolic activity and an organelle sequestering pro-apoptogenic intermediates, mitochondria lie at the crossroads of cellular decisions of death and survival. Intracellular calcium is a key regulator of these outcomes with rapid, uncontrolled uptake into mitochondria, activating...

Descripción completa

Detalles Bibliográficos
Autores principales: Saini, Neetu, Lakshminarayanan, Sowmya, Kundu, Priyanka, Sarin, Apurva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866856/
https://www.ncbi.nlm.nih.gov/pubmed/35222416
http://dx.doi.org/10.3389/fimmu.2022.832159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866856/
https://www.ncbi.nlm.nih.gov/pubmed/35222416
http://dx.doi.org/10.3389/fimmu.2022.832159

Ejemplares similares