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Notch1 Modulation of Cellular Calcium Regulates Mitochondrial Metabolism and Anti-Apoptotic Activity in T-Regulatory Cells

As the major hub of metabolic activity and an organelle sequestering pro-apoptogenic intermediates, mitochondria lie at the crossroads of cellular decisions of death and survival. Intracellular calcium is a key regulator of these outcomes with rapid, uncontrolled uptake into mitochondria, activating...

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Detalles Bibliográficos
Autores principales:	Saini, Neetu, Lakshminarayanan, Sowmya, Kundu, Priyanka, Sarin, Apurva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866856/ https://www.ncbi.nlm.nih.gov/pubmed/35222416 http://dx.doi.org/10.3389/fimmu.2022.832159

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