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Genome-wide Interaction Study Implicates VGLL2 and Alcohol Exposure and PRL and Smoking in Orofacial Cleft Risk

Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect, affecting approximately 1 in 700 births. NSCL/P has complex etiology including several known genes and environmental factors; however, known genetic risk variants only account for a small fraction of the heritabi...

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Detalles Bibliográficos
Autores principales: Carlson, Jenna C., Shaffer, John R., Deleyiannis, Fred, Hecht, Jacqueline T., Wehby, George L., Christensen, Kaare, Feingold, Eleanor, Weinberg, Seth M., Marazita, Mary L., Leslie, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866867/
https://www.ncbi.nlm.nih.gov/pubmed/35223824
http://dx.doi.org/10.3389/fcell.2022.621261