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Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms

Perturbations to the epigenome are known drivers of tumorigenesis. In melanoma, alterations in histone methyltransferases that catalyze methylation at histone 3 lysine 9 and histone 3 lysine 27—two sites of critical post-translational modification—have been reported. To study the function of these m...

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Detalles Bibliográficos
Autores principales: DiNapoli, Sara E., Martinez-McFaline, Raúl, Shen, Hao, Doane, Ashley S., Perez, Alexendar R., Verma, Akanksha, Simon, Amanda, Nelson, Isabel, Balgobin, Courtney A., Bourque, Caitlin T., Yao, Jun, Raman, Renuka, Béguelin, Wendy, Zippin, Jonathan H., Elemento, Olivier, Melnick, Ari M., Houvras, Yariv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866878/
https://www.ncbi.nlm.nih.gov/pubmed/35223844
http://dx.doi.org/10.3389/fcell.2022.814216