Cargando…

Impact of polymorphisms of pharmacokinetics‐related genes and the inflammatory response on the metabolism of voriconazole

The effects of inflammatory responses and polymorphisms of the genes encoding cytochrome P450 (CYP) (CYP2C19 and CYP3A5), flavin‐containing monooxygenase 3 (FMO3), pregnane X receptor (NR1I2), constitutive androstane receptor (NR1I3), and CYP oxidoreductase (POR) on the ratio of voriconazole (VRCZ)...

Descripción completa

Detalles Bibliográficos
Autores principales: Aiuchi, Naoya, Nakagawa, Junichi, Sakuraba, Hirotake, Takahata, Takenori, Kamata, Kosuke, Saito, Norihiro, Ueno, Kayo, Ishiyama, Masahiro, Yamagata, Kazufumi, Kayaba, Hiroyuki, Niioka, Takenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866912/
https://www.ncbi.nlm.nih.gov/pubmed/35199485
http://dx.doi.org/10.1002/prp2.935