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Impact of polymorphisms of pharmacokinetics‐related genes and the inflammatory response on the metabolism of voriconazole
The effects of inflammatory responses and polymorphisms of the genes encoding cytochrome P450 (CYP) (CYP2C19 and CYP3A5), flavin‐containing monooxygenase 3 (FMO3), pregnane X receptor (NR1I2), constitutive androstane receptor (NR1I3), and CYP oxidoreductase (POR) on the ratio of voriconazole (VRCZ)...
Autores principales: | Aiuchi, Naoya, Nakagawa, Junichi, Sakuraba, Hirotake, Takahata, Takenori, Kamata, Kosuke, Saito, Norihiro, Ueno, Kayo, Ishiyama, Masahiro, Yamagata, Kazufumi, Kayaba, Hiroyuki, Niioka, Takenori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866912/ https://www.ncbi.nlm.nih.gov/pubmed/35199485 http://dx.doi.org/10.1002/prp2.935 |
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