AKT Hyperphosphorylation and T Cell Exhaustion in Down Syndrome

Down syndrome (DS) is associated with increased susceptibility to infections, auto-immunity, immunodeficiency and haematological malignancies. The exact underlying immunological pathophysiology is still unclear. The immunophenotype and clinical characteristics of DS resemble those of Activated PI3K...

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Detalles Bibliográficos
Autores principales: Peeters, Daphne, Pico-Knijnenburg, Ingrid, Wieringa, Douwe, Rad, Mandana, Cuperus, Roos, Ruige, Madelon, Froeling, Frank, Zijp, Gerda W., van der Burg, Mirjam, Driessen, Gertjan J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866941/
https://www.ncbi.nlm.nih.gov/pubmed/35222360
http://dx.doi.org/10.3389/fimmu.2022.724436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866941/
https://www.ncbi.nlm.nih.gov/pubmed/35222360
http://dx.doi.org/10.3389/fimmu.2022.724436

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