The Mechanotransduction Channel and Organic Cation Transporter Are Critical for Cisplatin Ototoxicity in Murine Hair Cells

Cisplatin is one of the most widely used chemotherapeutic drugs across the world. However, the serious ototoxic effects, leading to permanent hair cell death and hearing loss, significantly limit the utility of cisplatin. In zebrafish, the functional mechanotransduction channel is required for cispl...

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Detalles Bibliográficos
Autores principales: Li, Jinan, Liu, Chang, Kaefer, Samuel, Youssef, Mariam, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866953/
https://www.ncbi.nlm.nih.gov/pubmed/35221917
http://dx.doi.org/10.3389/fnmol.2022.835448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866953/
https://www.ncbi.nlm.nih.gov/pubmed/35221917
http://dx.doi.org/10.3389/fnmol.2022.835448

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