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The Mechanotransduction Channel and Organic Cation Transporter Are Critical for Cisplatin Ototoxicity in Murine Hair Cells
Cisplatin is one of the most widely used chemotherapeutic drugs across the world. However, the serious ototoxic effects, leading to permanent hair cell death and hearing loss, significantly limit the utility of cisplatin. In zebrafish, the functional mechanotransduction channel is required for cispl...
Autores principales: | Li, Jinan, Liu, Chang, Kaefer, Samuel, Youssef, Mariam, Zhao, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866953/ https://www.ncbi.nlm.nih.gov/pubmed/35221917 http://dx.doi.org/10.3389/fnmol.2022.835448 |
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