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Histone Deacetylase Isoforms Differentially Modulate Inflammatory and Autoantibody Responses in a Mouse Model of Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune disease characterized by chronic muscle fatigue and weakness caused by autoantibodies and complement-mediated damage at neuromuscular junctions. Histone deacetylases (HDACs) are crucial epigenetic regulators of proinflammatory gene expression; however, it is u...

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Detalles Bibliográficos
Autores principales: Bahauddin, Afrin, Ivannikov, Maxim, Wang, Zhongying, Jamaluddin, Mohammad, Curtis, Kyra, Ibtehaj, Naazneen, Yeager, Linsey, Soong, Lynn, Fang, Xiang, Huda, Ruksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866970/
https://www.ncbi.nlm.nih.gov/pubmed/35222229
http://dx.doi.org/10.3389/fneur.2021.804113