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T Cell Recognition of Tumor Neoantigens and Insights Into T Cell Immunotherapy
In cancer, non-synonymous DNA base changes alter protein sequence and produce neoantigens that are detected by the immune system. For immune detection, neoantigens must first be presented on class I or II human leukocyte antigens (HLA) followed by recognition by peptide-specific receptors, exemplifi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867076/ https://www.ncbi.nlm.nih.gov/pubmed/35222422 http://dx.doi.org/10.3389/fimmu.2022.833017 |