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Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling

Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) is a lipid kinase that plays a pivotal role in the regulation of receptor-mediated calcium signaling in multiple tissues; however, its role in the skeleton is not clear. Here, we show that while deleting Pip5k1c expression in the mesen...

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Detalles Bibliográficos
Autores principales: Yan, Qinnan, Gao, Huanqing, Yao, Qing, Ling, Kun, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867119/
https://www.ncbi.nlm.nih.gov/pubmed/35090892
http://dx.doi.org/10.1016/j.jbc.2022.101639