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Type 1 interferon status in systemic lupus erythematosus: a longitudinal analysis

OBJECTIVES: Type 1 interferon (IFN) is key to the pathogenesis of SLE, evidenced by the expression of IFN-stimulated genes (ISGs) in most patients, but the clinical utility of serial ISG assessment remains unknown. With the emergence of IFN-blocking drugs, we aimed to examine IFN status in relation...

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Detalles Bibliográficos
Autores principales: Northcott, Melissa, Jones, Sarah, Koelmeyer, Rachel, Bonin, Julie, Vincent, Fabien, Kandane-Rathnayake, Rangi, Hoi, Alberta, Morand, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867321/
https://www.ncbi.nlm.nih.gov/pubmed/35197305
http://dx.doi.org/10.1136/lupus-2021-000625