Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2)

[Image: see text] Many industrial processes operate at elevated temperatures or within broad pH and salinity ranges. However, the utilization of enzymes to carry out biocatalysis in such processes is often impractical or even impossible. Laccases (EC 1.10.3.2), which constitute a large family of mul...

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Detalles Bibliográficos
Autores principales: Zovo, Kairit, Pupart, Hegne, Van Wieren, Arie, Gillilan, Richard E., Huang, Qingqiu, Majumdar, Sudipta, Lukk, Tiit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867573/
https://www.ncbi.nlm.nih.gov/pubmed/35224382
http://dx.doi.org/10.1021/acsomega.1c06668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867573/
https://www.ncbi.nlm.nih.gov/pubmed/35224382
http://dx.doi.org/10.1021/acsomega.1c06668

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