Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

BACKGROUND: Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in tumorigenesis. However, the mechanism underling Drp...

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Detalles Bibliográficos
Autores principales: Li, Yujia, Chen, Hui, Yang, Qi, Wan, Lixin, Zhao, Jing, Wu, Yuanyuan, Wang, Jiaxin, Yang, Yating, Niu, Menglan, Liu, Hongliang, Liu, Junqi, Yang, Hushan, Wan, Shaogui, Wang, Yanming, Bao, Dengke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867650/
https://www.ncbi.nlm.nih.gov/pubmed/35209954
http://dx.doi.org/10.1186/s13046-022-02262-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867650/
https://www.ncbi.nlm.nih.gov/pubmed/35209954
http://dx.doi.org/10.1186/s13046-022-02262-z

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