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Important role of the SDF-1/CXCR4 axis in the homing of systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) to ovaries in rats with chemotherapy-induced premature ovarian insufficiency (POI)

BACKGROUND: Chemotherapy can induce premature ovarian insufficiency (POI). POI causes multiple sequelae and is currently incurable. As shown in our previous studies, systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) home to ovaries with chemotherapy-induced POI and sub...

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Detalles Bibliográficos
Autores principales: Ling, Li, Hou, Jiying, Liu, Dandan, Tang, Dongyuan, Zhang, Yanqin, Zeng, Qianru, Pan, Heng, Fan, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867754/
https://www.ncbi.nlm.nih.gov/pubmed/35197118
http://dx.doi.org/10.1186/s13287-022-02759-6