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Neuronal FcεRIα directly mediates ocular itch via IgE-immune complex in a mouse model of allergic conjunctivitis

BACKGROUND: Classical understanding of allergic conjunctivitis (ACJ) suggests that ocular itch results from a mast cell-dependent inflammatory process. However, treatments that target inflammatory mediators or immune cells are often unsatisfying in relieving the stubborn itch symptom. This suggests...

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Detalles Bibliográficos
Autores principales: Cui, Huan, Liu, Fan, Fang, Yehong, Wang, Tao, Yuan, Bo, Ma, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867756/
https://www.ncbi.nlm.nih.gov/pubmed/35197064
http://dx.doi.org/10.1186/s12974-022-02417-x