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Compositional Data Analysis using Kernels in mass cytometry data

MOTIVATION: Cell-type abundance data arising from mass cytometry experiments are compositional in nature. Classical association tests do not apply to the compositional data due to their non-Euclidean nature. Existing methods for analysis of cell type abundance data suffer from several limitations fo...

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Detalles Bibliográficos
Autores principales: Rudra, Pratyaydipta, Baxter, Ryan, Hsieh, Elena W Y, Ghosh, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867823/
https://www.ncbi.nlm.nih.gov/pubmed/35224501
http://dx.doi.org/10.1093/bioadv/vbac003