Cargando…
Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine
OBJECTIVE: This study aims to prepare candidate vaccines for cervical cancer immunotherapy by inserting the fused genes of human papillomavirus (HPV)16/18/58 mE6E7 lacking transforming activity into an adenovirus vector and to verify its efficiency in model mice with tumor expressing the associated...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867827/ https://www.ncbi.nlm.nih.gov/pubmed/35197089 http://dx.doi.org/10.1186/s13027-022-00417-3 |