Cargando…

Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine

OBJECTIVE: This study aims to prepare candidate vaccines for cervical cancer immunotherapy by inserting the fused genes of human papillomavirus (HPV)16/18/58 mE6E7 lacking transforming activity into an adenovirus vector and to verify its efficiency in model mice with tumor expressing the associated...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Bing, Qin, Lu, Ma, Weihong, Wang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867827/
https://www.ncbi.nlm.nih.gov/pubmed/35197089
http://dx.doi.org/10.1186/s13027-022-00417-3