Cargando…

Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine

OBJECTIVE: This study aims to prepare candidate vaccines for cervical cancer immunotherapy by inserting the fused genes of human papillomavirus (HPV)16/18/58 mE6E7 lacking transforming activity into an adenovirus vector and to verify its efficiency in model mice with tumor expressing the associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wan, Bing, Qin, Lu, Ma, Weihong, Wang, He
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867827/ https://www.ncbi.nlm.nih.gov/pubmed/35197089 http://dx.doi.org/10.1186/s13027-022-00417-3

Ejemplares similares

A novel trivalent HPV 16/18/58 vaccine with anti-HPV 16 and 18 neutralizing antibody responses comparable to those induced by the Gardasil quadrivalent vaccine in rhesus macaque model
por: Yin, Fei, et al.
Publicado: (2017)

Stability of trivalent human papillomavirus (types 16, 18, 58) recombinant vaccine (Escherichia coli)
por: Liu, Yu-Ying, et al.
Publicado: (2021)

Cross-neutralizing antibody titres against non-vaccine types induced by a recombinant trivalent HPV vaccine (16/18/58) in rhesus macaques
por: Wang, Yan, et al.
Publicado: (2020)

The levels of anti-HPV16/18 and anti-HPV31/33/35/45/52/58 antibodies among AS04-adjuvanted HPV16/18 vaccinated and non-vaccinated Ugandan girls aged 10–16 years
por: Nakalembe, Miriam, et al.
Publicado: (2014)

Genotyping for Human Papillomavirus (HPV) 16/18/52/58 Has a Higher Performance than HPV16/18 Genotyping in Triaging Women with Positive High-risk HPV Test in Northern Thailand
por: Khunamornpong, Surapan, et al.
Publicado: (2016)

Evolution and Taxonomic Classification of Human Papillomavirus 16 (HPV16)-Related Variant Genomes: HPV31, HPV33, HPV35, HPV52, HPV58 and HPV67
por: Chen, Zigui, et al.
Publicado: (2011)

Adenovirus-Based Vectors for the Development of Prophylactic and Therapeutic Vaccines
por: Borovjagin, Anton V., et al.
Publicado: (2014)

Adenoviruses as vaccine vectors
por: Tatsis, Nia, et al.
Publicado: (2004)

Characterization of recombinant gorilla adenovirus HPV therapeutic vaccine PRGN-2009
por: Pellom, Samuel T., et al.
Publicado: (2021)

Genetic Variability in L1 and L2 Genes of HPV-16 and HPV-58 in Southwest China
por: Yue, Yaofei, et al.
Publicado: (2013)

Construction and Characterization of a Novel Recombinant Attenuated and Replication-Deficient Candidate Human Adenovirus Type 3 Vaccine: “Adenovirus Vaccine Within an Adenovirus Vector”
por: Yan, Yuqian, et al.
Publicado: (2020)

Development of a Trivalent Construct Omp18/AhpC/FlgH Multi Epitope Peptide Vaccine Against Campylobacter jejuni
por: Lou, Hongqiang, et al.
Publicado: (2022)

Simian adenoviruses as vaccine vectors
por: Morris, Susan J, et al.
Publicado: (2016)

Is It Time to Genotype Beyond HPV16 and HPV18 for Cervical Cancer Screening?
por: Chua, Brandon Wen Bing, et al.
Publicado: (2022)

Burden of Human Papillomavirus (HPV)-Related Cancers Attributable to HPVs 6/11/16/18/31/33/45/52 and 58
por: de Sanjosé, Silvia, et al.
Publicado: (2019)

HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix
por: Long, Wenbo, et al.
Publicado: (2018)

Analysis of E2 gene integrity in HPV16 and HPV58 viruses isolated from women with cervical pathology
por: González-Losa, María del R, et al.
Publicado: (2016)

Characteristics of human papillomavirus infection among females and the genetic variations of HPV18 and HPV58 in Henan province, China
por: Wang, Ying, et al.
Publicado: (2023)

Construction and detection of the tissue-specific pINV-HPV16 E6/7 vector
por: GAO, HUI, et al.
Publicado: (2015)

Peak neutralizing and cross-neutralizing antibody levels to human papillomavirus types 6/16/18/31/33/45/52/58 induced by bivalent and quadrivalent HPV vaccines
por: Mariz, Filipe Colaço, et al.
Publicado: (2020)

Prevalence of HPV 16 and HPV 18 Lineages in Galicia, Spain
por: Pérez, Sonia, et al.
Publicado: (2014)

Development of nonhuman adenoviruses as vaccine vectors
por: Bangari, Dinesh S., et al.
Publicado: (2006)

A new generation needle- and adjuvant-free trivalent plague vaccine utilizing adenovirus-5 nanoparticle platform
por: Kilgore, Paul B., et al.
Publicado: (2021)

Human papillomavirus (HPV) vaccination for the prevention of HPV 16/18 induced cervical cancer and its precursors
por: Damm, Oliver, et al.
Publicado: (2009)

Prevalence of HPV 16 and 18 and attitudes toward HPV vaccination trials in patients with cervical cancer in Mali
por: Téguété, Ibrahima, et al.
Publicado: (2017)

Bivalent Human Papillomavirus (HPV) Vaccine Effectiveness Correlates With Phylogenetic Distance From HPV Vaccine Types 16 and 18
por: Bogaards, Johannes A, et al.
Publicado: (2019)

Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China
por: He, Jiaoyu, et al.
Publicado: (2019)

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens
por: Arribillaga, Laura, et al.
Publicado: (2020)

Significance of HPV-58 Infection in Women Who Are HPV-Positive, Cytology-Negative and Living in a Country with a High Prevalence of HPV-58 Infection
por: Song, Joon Seon, et al.
Publicado: (2013)

Restriction-Assembly: A Solution to Construct Novel Adenovirus Vector
por: Guo, Xiaojuan, et al.
Publicado: (2022)

Cervarix(™): a vaccine for the prevention of HPV 16, 18-associated cervical cancer
por: Monie, Archana, et al.
Publicado: (2008)

In silico design of a multi-epitope vaccine against HPV16/18
por: Sanami, Samira, et al.
Publicado: (2022)

Safety and immunogenicity of a bivalent HPV16/18 vaccine in Chinese females
por: Shi, Li-Wei, et al.
Publicado: (2023)

L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis
por: Chen, Zuyi, et al.
Publicado: (2016)

Adenoviruses as vectors for delivering vaccines to mucosal surfaces
por: Babiuk, L.A, et al.
Publicado: (2000)

Adenovirus Vectors: Excellent Tools for Vaccine Development
por: Chang, Jun
Publicado: (2021)

COVID-19 Vaccines Based on Adenovirus Vectors
por: Hasanpourghadi, Mohadeseh, et al.
Publicado: (2021)

Adenovirus vector-based vaccine for infectious diseases
por: Sakurai, Fuminori, et al.
Publicado: (2022)

Type-Specific Viral Load and Physical State of HPV Type 16, 18, and 58 as Diagnostic Biomarkers for High-Grade Squamous Intraepithelial Lesions or Cervical Cancer
por: Kim, Jongseung, et al.
Publicado: (2020)

Implications of Persistent HPV52 and HPV58 Positivity for the Management of Cervical Lesions
por: Yi, Baozhu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3gmojvpbi3vpv3gfu0s1o7nsc0