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Modulation of the tumor microenvironment by armed vesicular stomatitis virus in a syngeneic pancreatic cancer model
BACKGROUND: The immunosuppressive microenvironment in pancreatic ductal adenocarcinoma is a major factor that limits the benefits of immunotherapy, especially immune checkpoint blockade. One viable strategy for reverting the immunosuppressive conditions is the use of an oncolytic virus (OV) in combi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867845/ https://www.ncbi.nlm.nih.gov/pubmed/35197076 http://dx.doi.org/10.1186/s12985-022-01757-7 |