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Modulation of the tumor microenvironment by armed vesicular stomatitis virus in a syngeneic pancreatic cancer model

BACKGROUND: The immunosuppressive microenvironment in pancreatic ductal adenocarcinoma is a major factor that limits the benefits of immunotherapy, especially immune checkpoint blockade. One viable strategy for reverting the immunosuppressive conditions is the use of an oncolytic virus (OV) in combi...

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Detalles Bibliográficos
Autores principales:	Tang, Sijia, Shi, Lei, Luker, Breona T., Mickler, Channen, Suresh, Bhavana, Lesinski, Gregory B., Fan, Daping, Liu, Yuan, Luo, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867845/ https://www.ncbi.nlm.nih.gov/pubmed/35197076 http://dx.doi.org/10.1186/s12985-022-01757-7

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