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A mutation-based gene set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape
BACKGROUND: Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of many cancers. However, the limited population that benefits from ICI therapy makes it necessary to screen predictive biomarkers for stratifying patients. Currently, many biomarkers, such as tumor mutational bur...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867854/ https://www.ncbi.nlm.nih.gov/pubmed/35197093 http://dx.doi.org/10.1186/s13073-022-01024-y |