Cargando…

Viroporins: Structure, function, and their role in the life cycle of SARS-CoV-2

Viroporins are indispensable for viral replication. As intracellular ion channels they disturb pH gradients of organelles and allow Ca(2+) flux across ER membranes. Viroporins interact with numerous intracellular proteins and pathways and can trigger inflammatory responses. Thus, they are relevant t...

Descripción completa

Detalles Bibliográficos
Autores principales: Breitinger, Ulrike, Farag, Noha S., Sticht, Heinrich, Breitinger, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868010/
https://www.ncbi.nlm.nih.gov/pubmed/35219876
http://dx.doi.org/10.1016/j.biocel.2022.106185