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Stress-responsive regulation of extracellular proteostasis

Genetic, environmental, and aging-related insults can promote the misfolding and subsequent aggregation of secreted proteins implicated in the pathogenesis of numerous diseases. This has led to considerable interest in understanding the molecular mechanisms responsible for regulating proteostasis in...

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Detalles Bibliográficos
Autores principales: Mesgarzadeh, Jaleh S., Buxbaum, Joel N., Wiseman, R. Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868021/
https://www.ncbi.nlm.nih.gov/pubmed/35191945
http://dx.doi.org/10.1083/jcb.202112104