Cargando…
Stress-responsive regulation of extracellular proteostasis
Genetic, environmental, and aging-related insults can promote the misfolding and subsequent aggregation of secreted proteins implicated in the pathogenesis of numerous diseases. This has led to considerable interest in understanding the molecular mechanisms responsible for regulating proteostasis in...
Autores principales: | Mesgarzadeh, Jaleh S., Buxbaum, Joel N., Wiseman, R. Luke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868021/ https://www.ncbi.nlm.nih.gov/pubmed/35191945 http://dx.doi.org/10.1083/jcb.202112104 |
Ejemplares similares
-
PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress
por: Romine, Isabelle C., et al.
Publicado: (2019) -
ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors
por: Mesgarzadeh, Jaleh S., et al.
Publicado: (2022) -
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation
por: Plate, Lars, et al.
Publicado: (2016) -
Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3
por: Ibrahim, Lara, et al.
Publicado: (2020) -
Role of Proteostasis Regulation in the Turnover of Stress Granules
por: Hu, Rirong, et al.
Publicado: (2022)