Nitric Oxide Resistance in Leishmania (Viannia) braziliensis Involves Regulation of Glucose Consumption, Glutathione Metabolism and Abundance of Pentose Phosphate Pathway Enzymes

In American Tegumentary Leishmaniasis production of cytokines, reactive oxygen species and nitric oxide (NO) by host macrophages normally lead to parasite death. However, some Leishmania braziliensis strains exhibit natural NO resistance. NO-resistant strains cause more lesions and are frequently mo...

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Detalles Bibliográficos
Autores principales: Pinho, Nathalia, Bombaça, Ana Cristina, Wiśniewski, Jacek R., Dias-Lopes, Geovane, Saboia-Vahia, Leonardo, Cupolillo, Elisa, de Jesus, José Batista, de Almeida, Roque P., Padrón, Gabriel, Menna-Barreto, Rubem, Cuervo, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868067/
https://www.ncbi.nlm.nih.gov/pubmed/35204161
http://dx.doi.org/10.3390/antiox11020277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868067/
https://www.ncbi.nlm.nih.gov/pubmed/35204161
http://dx.doi.org/10.3390/antiox11020277

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