Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1

Cells that experience high levels of oxidative stress respond by inducing antioxidant proteins through activation of the protein transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2). Nrf2 is negatively regulated by the E3 ubiquitin ligase Kelch-like ECH-associated protein 1 (Keap1...

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Detalles Bibliográficos
Autores principales: Ngo, Vy, Karunatilleke, Nadun C., Brickenden, Anne, Choy, Wing-Yiu, Duennwald, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868093/
https://www.ncbi.nlm.nih.gov/pubmed/35204126
http://dx.doi.org/10.3390/antiox11020243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868093/
https://www.ncbi.nlm.nih.gov/pubmed/35204126
http://dx.doi.org/10.3390/antiox11020243

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