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Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1
Cells that experience high levels of oxidative stress respond by inducing antioxidant proteins through activation of the protein transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2). Nrf2 is negatively regulated by the E3 ubiquitin ligase Kelch-like ECH-associated protein 1 (Keap1...
Autores principales: | Ngo, Vy, Karunatilleke, Nadun C., Brickenden, Anne, Choy, Wing-Yiu, Duennwald, Martin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868093/ https://www.ncbi.nlm.nih.gov/pubmed/35204126 http://dx.doi.org/10.3390/antiox11020243 |
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